Multiple myeloma: causes and consequences of delay in diagnosis

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Multiple myeloma: causes and consequences of delay in diagnosis.

BACKGROUND Myeloma is a serious and usually fatal haematological malignancy with reported mortality of 10-20% within the first 2 months of presentation. Symptoms are non-specific, and patients thus present to a range of medical practitioners. AIM To analyse the causes and consequences of a delay in diagnosis of myeloma. DESIGN Retrospective case review. METHODS The number and type of dise...

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In recent decades, new serum biomarkers have been developed for routine laboratory practice, such as assaying serum free light chains and more recently, assaying immunoglobulin heavy and light chain isotypes (Hevylite). In this work, we highlight the interest of new biomarkers (Hevylite Test) in the management of monoclonal gammopathies because of the technical advantages it confers and the se...

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ژورنال

عنوان ژورنال: QJM

سال: 2007

ISSN: 1460-2725,1460-2393

DOI: 10.1093/qjmed/hcm077